Juliflorine susceptibility of animal and human isolates of Campylobacter.

Juliflorine, the main alkaloid isolated from Prosopis juliflora was tested for its antibacterial activity against both the Gram positive and Gram negative bacteria. Filter paper disks impregnated with juliflorine were placed on streaked agar medium. Zones of growth inhibition for Campylobacter spp occurred at 10 pg per disk. Other enteropathogens (including the species of Salmonella, Shigella, Vibrio, Eseherichia, Proteus, Pseudomonas, Klebsiella and Yersinia) were resistant to at least 30 pg per disk, with the exception of a strain of Aeromonas hydrophilia, which showed some inhibition at 30 pg per disk. Most of the 25 Campylobacter strains, which were isolated from human clinical and animal sources, showed zones of inhibition greater than 10mm with 10 pg of juliflorine (JPMA 38: 20 , 1988).